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What makes Novavax an alternative to mRNA vaccines

What makes Novavax an alternative to mRNA vaccines

COVID-19 vaccines have been a monumental step in the global fight against the pandemic. Some vaccines have utilized mRNA technology, which has helped in preventing severe illness and reducing transmission. However, some individuals have experienced adverse reactions to these, raising questions about alternative options. One alternative is the Novavax COVID-19 vaccine. It uses a different mechanism than mRNA vaccines, making it a potential choice for those who have experienced adverse reactions to the mRNA options.

Understanding the Differences

mRNA Vaccines
These vaccines work by introducing a small piece of the virus’s mRNA into the body, instructing cells to produce a harmless spike protein. The immune system then recognizes this protein and creates antibodies to fight it. These antibodies are primed to combat the actual virus if the individual is exposed.

Novavax Vaccine
The Novavax vaccine, known as NVX-CoV2373, employs a protein subunit approach. It contains a tiny piece of the spike protein that’s found on the surface of the SARS-CoV-2 virus. When administered, it triggers an immune response, producing antibodies that can recognize and neutralize the spike protein if the person is later exposed to the virus.

Why Consider Novavax for Those with Adverse Reactions?

Different Mechanism
Novavax’s protein subunit vaccine operates differently from mRNA vaccines. For individuals who experienced adverse reactions to mRNA vaccines, switching to a vaccine with an alternate mechanism may reduce the risk of recurring reactions.

Important considerations prior to opting for Novavax vaccine

Consulting Healthcare Providers
Individuals who have experienced adverse reactions to mRNA vaccines should consult their healthcare providers before making any decisions about switching to the Novavax vaccine or any other alternative. Healthcare providers can offer personalized guidance based on an individual’s risk factors and medical history.

Vaccine Availability
Availability of vaccines may vary by location and time. Not all regions may offer the Novavax vaccine, so individuals should check with local health authorities for information on vaccine options.

Monitoring Data
As more data becomes available about the Novavax vaccine’s safety and efficacy, it will be important to stay informed. Regulatory agencies such as the FDA closely monitor vaccine performance and provide updates accordingly.

Sources:

Comparing the COVID-19 Vaccines: How Are They Different? > News > Yale Medicine

The Novavax vaccine against COVID-19: What you need to know (who.int)

What sets apart Novavax option from other COVID-19 vaccines | American Medical Association (ama-assn.org)

What You Need to Know About the Novavax Protein-Based Vaccine | Johns Hopkins | Bloomberg School of Public Health (jhu.edu)

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